Nutritional Follow up After Hospital Discharge for Coronavirus Disease-19

• Conditions: Covid-19
• Interventions: Other: nutritional intervention

• Registration Number: NCT04451694
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

Coronavirus infection is responsible for muscle wasting (sarcopenia), especially during prolonged stays in intensive care. Sarcopenia, in its functional aspect also seems major in patients hospitalized for this infection, in non-ICU unit. Weight loss also appears to be significant, despite a prevalence of overweight and obesity in severe forms. Undernutrition in the obese patient is also possible (undernourished obese and sarcopenia obesity). Anosmia and dysgeusia participate in undernutrition by reducing energy intake. The rehabilitation of these patients requires nutritional support (increased protein intake) associated with progressive retraining to physical activity.

An early and proactive management procedure within Coronavirus disease-19 units has been implemented in conjunction with the Transversal Nutrition Unit (TNU). This nutritional care must be continued after discharge. Follow-up by teleconsultation or telephone consultation is put in place after the patient's discharge Primary Objective: Evaluation of nutritional status at the time of admission and discharge and home follow-up in outgoing patients from Coronavirus disease-19 Units Secondary objectives: Description of the evolution of food intake, diversity of food and coverage of needs Evaluation of the muscular strength of the wrist (by grip test in hospital) and on the arms and legs after return home (visual analog scale) Evolution of anosmia and dysgeusia (at the time of hospital admission, at the time of hospital discharge and at home) Level of physical training before infection (IPAQ) Description of the general state of health measured by the performance index - world health organization scale Description of nutritional prescriptions Description of the prevention measures and incidence of Inappropriate Refeeding Syndrome (IRS) Care needs assessments

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-01
• Status Verified: 2020-06
• Study First Submitted: 2020-06-15
• Study First Submitted QC: 2020-06-25
• Last Update Submitted: 2020-06-25
• Study First Posted: 2020-06-30
• Last Update Posted: 2020-06-30
• Primary Completion: 2020-07-30
• Study Completion: 2020-11-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• Covid positive (RT-PCR)

Exclusion Criteria

• Unable to answer questions by telephone or teleconsultation directly or through a relative, minors under 16 years of age

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Covid-19 unit outgoing patients	nutritional intervention	nutritional evaluation and intervention

Primary Outcome Measures

Name	Time	Method
nutritional evaluation	before Covid, at at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge	BMI

Secondary Outcome Measures

Name	Time	Method
muscle strenght	between 7 and 45 days after discharge	self evaluation of muscle strenght
food intake	between 7 and 45 days after discharge	self evaluation of food intake
biological nutritional status	at the time of hospital admission, at the time of hospital discharge	albuminemia transthyretinemia electrolytes dosage inflammation status
anosmia	at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge	anosmia and agueusia evolution

Trial Locations

Locations (1)

Quilliot; 🇫🇷 VANDOEUVRE LES Nancy, France