NL-OMON51753招募中不适用
Effect of pasteurized Akkermansia muciniphila on maintenance of body weight after a low caloric diet - Akkermansia and weight maintenance
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 108
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •Overweight/obese (BMI >= 28 kg/m2 < 40 kg/m2) men and women
排除标准
- •- diabetes mellitus
- •- gastroenterological diseases or major abdominal surgery (allowed i.e.:
- •appendectomy, cholecystectomy)
- •- lactose intolerance and other digestive disorders
- •- cardiovascular disease, cancer, liver or kidney malfunction (determined based
- •on ALAT and creatinine levels,
- •respectively)
- •- disease with a life expectancy shorter than 5 years
- •- abuse of products (alcohol consumption > 15 units/week, or any drugs)
- •- excessive nicotine use defined as >20 cigarettes per day
- •- plans to lose weight or follow a hypocaloric diet
- •- regular supplement of pre- or probiotic products
- •- intensive exercise more than three hours a week
- •- Use of any medication that influences glucose or fat metabolism, like
- •lipidlowering-drugs (e.g. PPAR γ or PPARa (fibrates) agonists),
- •glucose-lowering agents (including allsulfonylureas, biguanides, a-glucosidase
- •inhibitors, thiazolidinediones, repaglinide, nateglinide and insulin),
- •inflammation (e.g. anti-inflammatory or immunosuppressive drugs) and
- •anti-oxidants;
- •- use of laxation products in the last three months or during the study period-
- •Suikerziekte heeft;
- •- Pregnancy and lactation
研究者
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