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临床试验/NL-OMON51753
NL-OMON51753招募中不适用

Effect of pasteurized Akkermansia muciniphila on maintenance of body weight after a low caloric diet - Akkermansia and weight maintenance

niversiteit Maastricht0 个研究点目标入组 108 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
108

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • Overweight/obese (BMI >= 28 kg/m2 < 40 kg/m2) men and women

排除标准

  • - diabetes mellitus
  • - gastroenterological diseases or major abdominal surgery (allowed i.e.:
  • appendectomy, cholecystectomy)
  • - lactose intolerance and other digestive disorders
  • - cardiovascular disease, cancer, liver or kidney malfunction (determined based
  • on ALAT and creatinine levels,
  • respectively)
  • - disease with a life expectancy shorter than 5 years
  • - abuse of products (alcohol consumption > 15 units/week, or any drugs)
  • - excessive nicotine use defined as >20 cigarettes per day
  • - plans to lose weight or follow a hypocaloric diet
  • - regular supplement of pre- or probiotic products
  • - intensive exercise more than three hours a week
  • - Use of any medication that influences glucose or fat metabolism, like
  • lipidlowering-drugs (e.g. PPAR γ or PPARa (fibrates) agonists),
  • glucose-lowering agents (including allsulfonylureas, biguanides, a-glucosidase
  • inhibitors, thiazolidinediones, repaglinide, nateglinide and insulin),
  • inflammation (e.g. anti-inflammatory or immunosuppressive drugs) and
  • anti-oxidants;
  • - use of laxation products in the last three months or during the study period-
  • Suikerziekte heeft;
  • - Pregnancy and lactation

研究者

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