ACTRN12614000790640
Completed
Phase 4
A prospective randomised trial of intraoperative tidal volume ventilation with 6ml/kg (Ideal Body weight) and positive end expiratory pressure (PEEP) of 5 cm H2O versus 10ml/kg (Ideal Body weight) and PEEP of 5 cm H2O, in adult patients undergoing major surgery.
Departments of Intensive Care and Anaesthesia, Austin Hospital0 sites1,240 target enrollmentJuly 24, 2014
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Effects of ventilation in patients undergoing major surgery
- Sponsor
- Departments of Intensive Care and Anaesthesia, Austin Hospital
- Enrollment
- 1240
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients will be eligible to participate in this study if:
- •1\. The patient is aged 40 years or older
- •2\. The treating anaesthetist expects that the patient will remain intubated for a period of equal to or greater than two hours
- •3\. The patient will have an arterial line inserted for routine monitoring of blood pressure during the surgical procedure
Exclusion Criteria
- •Patients will be ineligible for participation if:
- •1\. The patient is pregnant and/or lactating
- •2\. The patient has planned thoracic surgery
- •3\. The patient has planned cardiac surgery
- •4\. The patient has planned intracranial neurosurgery
- •5\. Previously enrolment in this Trial
Outcomes
Primary Outcomes
Not specified
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