The effect of aggressive hydration for prevention of post-ERCP pancreatitis

Chonnam National University Hospital0 个研究点目标入组 432 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

暂无简介。

•High-risk for post Endoscopic Retrograde Cholangio-Pancreatography (ERCP) pancreatitis ( at least one of the items)
•- under 40 years old
•- Sphincter Oddi dysfunction
•- normal bilirubin blood level
•- past history of recurrent pancreatitis
•- past history of post Endoscopic Retrograde Cholangio-Pancreatography (ERCP) pancreatitis
•- In case of necessity for ductal injection of contrast media
•- In case of necessity for sphinceterotomy
•- in case of necessity for pre-cut sphincertomy
•- in case of necessity for balloon dilatation of sphincter

•Exclusion criteria ( at least one of the items)
•- Patient without agreement
•- <20yrs old or >80yrs old
•- severe mental illness
•- severe comorbidities ( End-stage renal disease, Advanced Chronic obstructive pulmonary disease, severe heart failure, poorly controlled blood sugar, Etc)
•- septicemia (at least two of the following)
•-Temperature >38.3 or <36ºc
•-Heart rate >90 beats/min
•-Tachypnea, respiratory rate > 20 breaths/min
•-Leukocytosis (White blood cell > 12,000 microL-1 ) or Leukopenia (White blood cell < 4000 microL-1)
•- acute pancreatitis
•- chronic pancreatitis
•- heart failure ( >NYHA class 2)
•- clinical sign of volume overload
•- hypernatremia (>150 mEq/L) and/or hyponatremia (<130mEq/L)
•- past history of endoscopic sphicterotomy
•- past history of balloon dilatation of ampulla of vater
•- hypercalcemia and/or metabolic alkalosis

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