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Clinical Trials/NCT06737198
NCT06737198Active, not recruitingNot Applicable

Correlation of Preoperative Indices (serum Vit D, Calcium, Phosphorus, FAR, PLR, SII) on Intraoperative Bleeding in CRS

Nanjing First Hospital, Nanjing Medical University1 site in 1 country100 target enrollmentStarted: November 1, 2024Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Active, not recruiting
Enrollment
100
Locations
1
Primary Endpoint
Intraoperative haemorrhage

Study Overview

Brief Summary

The purpose of this observational study was to examine whether preoperative indicators correlate with intraoperative bleeding to facilitate control of intraoperative bleeding.

Detailed Description

In this study, we analysed the effect of preoperative inflammation on intraoperative haemorrhage at the subjective and objective levels by measuring a number of indicators (including Vit D, Ca, P, and some ratios) in the blood specimens and by three scales.Blood test indicators can be obtained from routine tests.Three scales were obtained by the researcher after interviewing the patients, Symptom Score (0-15), where higher scores indicate more severe symptoms, Lund-Kennedy Score (0-6), where higher scores indicate higher levels of localised inflammation, Lund-Mackay Score (0-12 unilaterally and 24 bilaterally), where higher scores indicate higher levels of inflammation, and Lund-Mackay Score (0-12 unilaterally and 24 bilaterally), where higher scores indicate higher levels of inflammation.Lund-Mackay score (0-12 unilaterally, 24 bilaterally), where higher scores represent higher levels of inflammation.Final correlation of blood test indices and three scale scores with intraoperative.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 70 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Clinical diagnosis of chronic rhinosinusitis

Exclusion Criteria

  • Sinus cyst Upper respiratory tract infection in the last 1 week Use of antiepileptic drugs Use of aspirin Use of anticoagulant or antiplatelet drugs

Outcomes

Primary Outcomes

Intraoperative haemorrhage

Time Frame: 2024/11/1-2025/7/31

Intraoperative haemorrhage was grouped with a cut-off value of 150 ml and divided into \<150 ml (normal haemorrhage group) and ≥150 ml (high haemorrhage group).

Secondary Outcomes

  • Symptom system(2024/11/1-2025/7/31)
  • Lund-Kennedy system(2024/11/1-2025/7/31)
  • Lund-Mackay system(2024/11/1-2025/7/31)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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