DRKS00025507已完成不适用

Investigation of immune cells in patients with obstructive sleep apnea - ImZellOSA

niversitätsmedizin der Johannes Gutenberg-Universität Mainz; Hals-, Nasen-, Ohrenklinik und Poliklinik0 个研究点目标入组 40 人开始时间: 2021年7月20日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patient in the Sleep Medicine Centre & Sleep Research Lab, Dept. of Otorhinolaryngology Head & Neck Surgery, University Medical Center Mainz;
•Willingness to participate in the study;
•Suspicion of Obstructive Sleep Apnea;
•Snoring or daytime sleepiness or observed breathing interruptions during sleep or an AHI = 5 / h screened by an outpatient cardiorespiratory polygraph;
•Currently no therapy for breathing-related sleep disorders (e.g. continuous positive airway pressure: CPAP);
•No prior surgical procedure for OSA;
•Age of the participant: > 18 years;
•German and / or English language skills

•Age of the participant: <18 years;
•Existing pregnancy;
•obesity (BMI> 35 kg / m²);
•COPD (chronic obstructive pulmonary disease);
•Heart failure;
•Active malignant disease (5 years after finishing the corresponding therapy);
•Hematological diseases (e.g. myelodysplastic syndrome);
•diagnosed immune deficiency (e.g. AIDS);
•Clinically relevant atherosclerosis (status post myocardial infarction, unstable angina pectoris, status post stroke, status post stenting of the coronary or peripheral arteries, status post surgery for peripheral arterial occlusive disease);
•Chronic active inflammatory diseases (psoriasis, rheumatoid arthritis, Wegener's disease, sarcoidosis, syst. Lupus erythemadotes, other autoimmune diseases);
•Active specific infections (e.g. tuberculosis);
•Chronic therapy with oral steroids, immunosuppressants (e.g. cyclophosphamide, azathioprine or antibodies (immunotherapy);
•Recently (within the last 4 weeks) history of vaccinations (e.g. against Covid-19)

发起方

niversitätsmedizin der Johannes Gutenberg-Universität Mainz; Hals-, Nasen-, Ohrenklinik und Poliklinik