Effect of Bromelain and Turmeric on orthodontic pai
Phase 3
- Conditions
- Evaluation of pain intensity after separator placement in orthodontics patients..
- Registration Number
- IRCT20181121041713N3
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 135
Inclusion Criteria
Need separator placement to begin orthodontic treatment in the maxillary arch
Aged 15 years or older
Not currently using antibiotics, analgesics, anti – inflammatory, anti-coagulative, diuretics, oral anti diabetics, lithium, cyclosporine and methotrexate
No need for antibiotic prophylaxis
Not pregnant or nursing
Exclusion Criteria
Extraction or missing of any maxillary teeth except from third molars
Smoking
Patients with chronic systemic diseases or clotting disorders
Reporting contraindication for NSAIDs, Bromelain and Turmeric
Reporting allergy to pineapple
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of pain intensity after elastic-separators placement in orthodontic patients. Timepoint: 2, 6, 24 and 48 hours after elastic-separators placement. Method of measurement: The Visual Analogue Scale (VAS) is used to determine the level of pain and discomfort.
- Secondary Outcome Measures
Name Time Method