A CLINICAL TRIAL TO STUDY THE EFFICACY OF TWO DRUGS, BROLUCIZUMAB AND AFLIBERCEPT IN PATIENTS WITH NEOVASCULAR AGE RELATED MACULAR DEGENERATION IN INDIAN POPULATIO
Not Applicable
Completed
- Conditions
- Health Condition 1: H353- Degeneration of macula and posterior pole
- Registration Number
- CTRI/2021/06/034415
- Lead Sponsor
- Army Hospital Research and ReferralDelhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 114
Inclusion Criteria
a.Typical morphology of Age-Related Macular Degeneration
b.Lesion affecting the central subfield (1 mm around centre)
c.Active Choroidal Neovascularization
d.CNV comprising more than 50% of total lesion area
e.Intraretinal or Subretinal Fluid in central subfield
f.BCVA between 20/32 to 20/400
Exclusion Criteria
a.Any Fibrosis or geographical atrophy of central subfield
b.Any intra or periocular infection or inflammation
c.Patient has received any approved treatment for nAMD other than micronutrient supplementation
d.Any concurrent intraocular disease like diabetic retinopathy
e.History of drug sensitivity/ Allergic reactions to research interventions
f.Stroke or MI in the 90 days preceding to baseline visit
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method