Jogging in the Change of Osteoporosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Osteoporosis
- Sponsor
- Peking University People's Hospital
- Enrollment
- 500
- Primary Endpoint
- DEXA T-score
- Last Updated
- 8 years ago
Overview
Brief Summary
To test the changes in osteoarthritis according to the X-rays, and changes in bone quality before and 1 or more years after beginning the jogging
Detailed Description
Patients in this research are given an entry Bone Densitometry（DEXA）scan and are required to advance from 3-minute jogging a day to 10-minute level in daily practice for 1 year as instructed. After 1 year, subsequent DEXA scans are recorded. Interested participants are also encouraged to have hip and spine X-rays, and bone quality studies on study entry and two years later. Actual subject participation, intercurrent illnesses, fractures and changes in medication are self-monitored. Results are calculated by change in bone mineral density in the lumbar spine, hips and femurs by the DEXA scan in the study. Dose-response relationships between the amount of jogging and bone mineral density are sought. Jogging-related fractures and other adverse effects are also noted.
Investigators
Zhang Yichong
Department of orthopaedics and trauma
Peking University People's Hospital
Eligibility Criteria
Inclusion Criteria
- •Past DEXA scan and, all within 6 months of study entry, DEXA scan and normal values for: Metabolic panel, TSH, PTH, ESR (or CRP), Vitamin D 25 hydroxy, Vitamin D 1,25 dihydroxy, Urine NTX
Exclusion Criteria
- •Known metabolic bone disease such as osteogenesis imperfecta, current treatment with steroids, chemotherapy, or currently healing fractures of lumbar spine, hips or femurs, severe heart disease
Outcomes
Primary Outcomes
DEXA T-score
Time Frame: 1 year
Bone mineral density change in spine, hip and femur after 1 year of jogging
Secondary Outcomes
- Number of fractures(1 year)