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Clinical Trials/ISRCTN44878718
ISRCTN44878718
Completed
Not Applicable

Age of BLood Evaluation (ABLE) trial in the resuscitation of critically ill patients: a multicentre randomised controlled superiority clinical trial

Sainte-Justine Hospital Research Centre (Centre de recherche du CHU Sainte-Justine) (Canada)0 sites2,510 target enrollmentAugust 22, 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Sainte-Justine Hospital Research Centre (Centre de recherche du CHU Sainte-Justine) (Canada)
Enrollment
2510
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 22, 2008
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Sainte-Justine Hospital Research Centre (Centre de recherche du CHU Sainte-Justine) (Canada)

Eligibility Criteria

Inclusion Criteria

  • Patients who:
  • 1\. Have had a request for a first red cell unit transfusion in the Intensive Care Unit (ICU), and
  • 2\. Have an anticipated length of invasive and/or non\-invasive continuous positive airway pressure (CPAP) or bi\-level positive airway pressure (BIPAP) mechanical ventilation of at least 48 hours once enrolled, as estimated by the attending physician

Exclusion Criteria

  • Investigators and research assistants will exclude patients:
  • 1\. Who are less than 16 years of age
  • 2\. Who were previously enrolled in the ABLE study
  • 3\. Who have already been transfused with red cells during the current hospitalisation
  • 4\. Who have an obvious terminal illness documented in the medical record with a life expectancy of less than 3 months
  • 5\. Who have undergone routine cardiac surgical care
  • 6\. Where a decision to withdraw/withhold some critical care had been made
  • 7\. Who are obviously brain dead
  • Investigators, research assistants and blood bank personnel will also exclude patients:
  • 8\. When there are no red cells with a storage time of 7 days or less available in the blood bank that cannot be transported from the blood supplier

Outcomes

Primary Outcomes

Not specified

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