Multivisceral Resections for Locally Advanced Gastric Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gastric Cancer
- Sponsor
- Jagiellonian University
- Enrollment
- 1476
- Locations
- 1
- Primary Endpoint
- Complications
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this observational study is to assess whether the postoperative course and survival of patients subject to multivisceral resections for locally advanced gastric cancer (cT4b) were affected by the extent of surgery. An electronic database of 1476 patients with non-metastatic gastric cancer treated between January 1996 and December 2020 will be reviewed. The main questions it aims to answer are:
- Does splenectomy, distal pancreatectomy or partial colectomy affect postoperative complications
- What factors affect prognosis of patients with locally advanced gastric cancer
Investigators
Marek Sierzega
Professor
Jagiellonian University
Eligibility Criteria
Inclusion Criteria
- •gastric adenocarcinoma
- •intraoperatively suspected infiltration of surrounding organs (stage cT4bN0-3bM0)
- •partial or total gastrectomy
Exclusion Criteria
- •distant metastases (M1)
- •gastrectomy combined with resection of organs other than spleen, pancreas, or colon
Outcomes
Primary Outcomes
Complications
Time Frame: up to 90 days
Type and severity of complications graded by Clavien-Dindo scoring system (from 0 to 5, higher scores mean worse outcome)
Survival
Time Frame: Overall survival from surgery to death or last follow up, whichever came first, assessed up to 60 months
Overall survival
Secondary Outcomes
- Rate of readmissions(One year from surgery)
- Length of postoperative hospital stay(Up to 6 months)
- Rate of reoperations(up to 90 days)