Evaluation of the Impact of Chemotherapy on Body Odor in Adolescents and Young Adults in Oncology

Completed

• Conditions: Solid Tumor, Adult; Chemotherapy Effect; Solid Tumor, Childhood
• Interventions: Other: Evaluation on appearance of unpleasant body odors

• Registration Number: NCT04899505
• Lead Sponsor: Institut Curie

Brief Summary

The appearance of unpleasant body odors in adolescent Young adult (aya) wille be evaluated undergoing chemotherapy

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-05-19
• Study First Submitted QC: 2021-05-19
• Study First Posted: 2021-05-24
• Study Start: 2021-10-21
• Status Verified: 2023-01
• Primary Completion: 2025-05-12
• Study Completion: 2025-05-12
• Last Update Submitted: 2025-05-14
• Last Update Posted: 2025-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

• Patients aged between 15 and 25 years;
• New patients treated at the Curie Institute and hospitalized in the AJA oncology department;
• Patient undergoing chemotherapy administered intravenously;
• Solid tumors.

Exclusion Criteria

• Patient undergoing oral chemotherapy;
• Persons deprived of their liberty or under guardianship (including guardianship);
• Inability to undergo medical monitoring of the trial for geographical, social or psychological reasons.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Evaluation on appearance of unpleasant body odors	Evaluation on appearance of unpleasant body odors	Incidence of the development of unpleasant body odors in AYA oncology patients

Primary Outcome Measures

Name	Time	Method
Incidence of the development of unpleasant body odors in AYA oncology patients	8 months	Percentage of patients reporting discomfort with unpleasant body odor that occurred during their treatment. This percentage will be calculated from the response to item Q1 of the patient questionnaire during the fourth course of chemotherapy in the AJA oncology department

Secondary Outcome Measures

Name	Time	Method
Quantification of the discomfort and the impact on quality of life	8 months	Answers to the investigation intended for patients to assess the intensity of the smell with a scale (0= no smell and 10 = strong smell) (Q4), its daily impact with a scale (0=no impact and 10= high impact) (Q7) and solutions that can reduce smell with different proposals like perfume, cream, essential oil (Q9)
Identify possible causes of the appearance of these new body odors	8 months	Answers to the investigation for patients to assess the link between smell and drug treatment with different proposals like treatment, hospital's food or hospital cleaning product (Q5 and Q6)
Qualification of the smell and the discomfort felt	8 months	Answers to the investigation intended for patients for the appearance of the smell with different proposals like sweating, urine, breath etc. (Q2), its qualifier with different proposals like desagreable, infective, nauseating, etc...(Q3) and the discomfort observed for themselves or for those around them (Q8)

Trial Locations

Locations (1)

Institut Curie; 🇫🇷 Paris, France