Effectiveness of Pulmonary Rehabilitation Program in Patients With SARS-CoV-2 Pneumonia
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 100
- Locations
- 2
- Primary Endpoint
- Change in functional capacity as measured by 30-second sit-to-stand test
Study Overview
Brief Summary
The aim of the study is to investigate the efficacy of pulmonary rehabilitation (PR) program to patients with Sars-CoV-2 pneumonia in the post-acute period on pulmonary functions, exercise capacity and anxiety level.
100 patients diagnosed with Sars-CoV-2 pneumonia will be enrolled in this prospective, interventional study according to inclusion/exclusion criteria. Patients will be evaluated and a personalized PR program will be organized before hospital discharge. After discharge, the pulmonary rehabilitation program will continue in telerehabilitation.
In the telerehabilitation program, exercises will be supervised by a physiotherapist two days a week, and patients will be asked to do the exercises themselves for the other 3 days. Patients will also receive exercise videos for these 3 days.
Patients will be followed for 4 weeks and will be called for final evaluation
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Pneumonia without having severe findings or a need for oxygen support therapy (mild pneumonia) accompanying special conditions (chronic lung / heart disease / diabetes / hypertension / neuromuscular disease history / elderly / immobility etc.)
- •Severe pneumonia (A suspicion of fever or respiratory tract infection and having one accompanying finding: respiration rate >30/min; severe respiratory distress; or SpO2 ≤93% in ambient air.) cases after they get clinically stable (decreased fever, reduced dyspnea, respiratory rate 90%)
- •At least 7 days since the diagnosis of SARS-CoV-2 in order to reduce the viral load and the risk of transmission
- •Being able to make video calls for telerehabilitation
Exclusion Criteria
- •Serious cardiovascular, cerebrovascular, neuromuscular and other systemic diseases that affect physical activity
- •Psychiatric illness and cognitive deficit that will affect patient's exercise cooperation
- •Pregnancy
- •The deterioration in the general condition of the patient, worsening of the lung findings
- •Acute respiratory distress syndrome
Outcomes
Primary Outcomes
Change in functional capacity as measured by 30-second sit-to-stand test
Time Frame: 4 weeks
30 sec- STS determines lower extremity strength and physical fitness in older adults. The number of repetitions is recorded.
Change in Dyspnea level as measured by modified Medical Research Council (mMRC) Dyspnea Scale
Time Frame: 4 weeks
The mMRC scale is a self-rating tool to measure the degree of disability that breathlessness poses on day-to-day activities on a scale from 0 to 4. 0: no breathlessness except on strenuous exercise; 4: too breathless to leave the house, or breathless when dressing or undressing.
Secondary Outcomes
- Change in physical activity level as measured by International Physical Activity Questionnaire (IPAQ) -Short Form(4 weeks)
- Change in anxiety and depression as measured by Hospital Anxiety and Depression Scale (HADS)(4 weeks)
Investigators
Enes Efe Is
MD
Sisli Hamidiye Etfal Training and Research Hospital