TCTR20210216003已完成4 期
Efficacy of Vonoprazan based dual therapy with amoxicillin versus standard triple therapy for Helicobacter pylori eradication in Thailand
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 128
研究概览
简要总结
7-days VA-dual regimen is non-inferiority than 14-days OAC-triple regimen as a first-line H. pylori eradication therapy and incidence of adverse events was a trend to lower in VA-dual subjects.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 75 Years（—）
- 性别
- All
入选标准
- •1) subjects undergoing gastrointestinal endoscopy at Department of Gastroenterology Phramongkutklao Hospital during 1 August 2019 to 28 February 2020
- •2) aged 18 years or over
- •3) diagnosis of H.pylori infection using upper GI endoscopy with the rapid urease test and positive test result of the infection.
排除标准
- •1) GFR <30 ml/min/1.73m2
- •2) history of drug resistance used in research studies
- •3) pregnant women or breastfeeding mothers
- •4) History treatment of H.pylori infection
- •5) Subjects in critical condition
- •6) Subjects to be diagnosed with neuroendocrine tumor, HIV infection
研究者
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