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A Randomized clinical study to check the inter-appointment pain in patients with infected teeth using two different combination of drugs

Phase 1
Completed
Conditions
Health Condition 1: K044- Acute apical periodontitis of pulpal origin
Registration Number
CTRI/2022/06/043007
Lead Sponsor
Dr DIKSHIT SOLANKI
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
72
Inclusion Criteria

Systemically healthy patients between age group of 18-60 years with maxillary or mandibular single rooted infected/necrotic teeth with symptomatic apical periodontitis will be included in the study.

Symptomatic chronic irreversible pulpitis with symptomatic apical periodontitis with loss of lamina dura will be included.

Symptomatic teeth showing presence of peri-apical radiolucency suggestive of periapical abscess will be included.

patients with pre-operative moderate to severe pain will be included.

A written informed consent will be taken and only those patients ready to sign the consent will be included in the study.

Exclusion Criteria

Asymptomatic teeth with periapical radiolucencies be it abscess or granuloma, etc will be excluded.

Medically compromised patients will be excluded.

Teeth with completely obliterated canals will be excluded.

Teeth with open apex, root resorption or complex root canal anatomy will be excluded.

Teeth with vertical root canal fractures, cracks, etc will be excluded.

Patients with deep periodontal disease or endo-perio lesion with periodontal phase dominant will be excluded.

Pregnant and lactating women will be excluded.

Patients using other medications such as analgesics or anti-inflammatory drugs during inter appointment will be excluded.

Patients allergic to antibiotics and anti-viral drugs will be excluded.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Interappointment pain assessmentTimepoint: 6hr,12 hr,24hr,3 days,6days
Secondary Outcome Measures
NameTimeMethod
efficacy of modified double antibiotic paste in pain managementTimepoint: 6hr,12 hr,24hr,3 days,6days
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