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Clinical Trials/NCT04648410
NCT04648410
Recruiting
Not Applicable

Administration of Systemic Corticosteroids Among Critically Ill Patients With COVID-19: Electronic Survey (ASAP-C Study)

Brno University Hospital1 site in 1 country2,000 target enrollmentFebruary 16, 2021
ConditionsSevere COVID-19

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Severe COVID-19
Sponsor
Brno University Hospital
Enrollment
2000
Locations
1
Primary Endpoint
Systemic corticosteroids among patients with COVID-19 ARDS practice - questionnaire (electronic survey)
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Administration of systemic corticosteroids for patients with severe forms of severe acute respiratory syndrome(SARS-Co-2) infection are recommended by several guidelines. In the very beginning of SARS-Co-2 pandemic the early recommendation by professional organization was against routine use of corticosteroids for patients with coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS), despite previous data and clinical practice for patients with refractory or severe form of ARDS.

Detailed Description

Administration of systemic corticosteroids for patients with severe forms of SARS-Co-2 infection are recommended by several guidelines. In the very beginning of SARS-Co-2 pandemic the early recommendation by professional organization was against routine use of corticosteroids for patients with coronavirus disease 2019 (COVID-19) ARDS, despite previous data and clinical practice for patients with refractory or severe form of ARDS. But at the latest after publication of RECOVERY trial (Randomized Evaluation of Covid-19 Therapy, July 2020) and ensued metaanalysis of World Health Organization (WHO) working group, the routine administration of systemic corticosteroids was revisited. However, there are ongoing critical debate of the evidence regarding the dose, administration, timing and type of corticosteroids and ongoing randomized controlled trial (RCT) are challenging the recommendation of 6 mg of dexamethasone for all patients with severe form of COVID-19. The dynamic of COVID-19 surges, flip-flop of official recommendations within very short period of time and ongoing critical debate could be with possible variations of daily clinical practice regarding using systemic corticosteroids. In an electronic evaluation form that will be send to European Society of Intensive Care (ESICM) Members. The electronic survey will contain 10 question. In the questionnaire the participants will have to describe their routine clinical practice regarding administration of systemic corticosteroids among patients with COVID-19 ARDS.

Registry
clinicaltrials.gov
Start Date
February 16, 2021
End Date
December 1, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Brno University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Petr Štourač, MD

assoc.prof.MD,Ph.D

Brno University Hospital

Eligibility Criteria

Inclusion Criteria

  • Members of European Society of Intensive Care

Exclusion Criteria

  • not members of European Society of Intensive Care

Outcomes

Primary Outcomes

Systemic corticosteroids among patients with COVID-19 ARDS practice - questionnaire (electronic survey)

Time Frame: 1 month

Administration of systemic corticosteroids among patients with COVID-19 ARDS practice in European countries - questionnaire (electronic survey)

Study Sites (1)

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