Skip to main content
Clinical Trials/NCT00991588
NCT00991588
Completed
Not Applicable

Reconstruction of the Posterior Cruciate Ligament and Posterolateral Structures of the Knee

Sue Barber-Westin1 site in 1 country20 target enrollmentOctober 2009
ConditionsKnee Injuries

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Injuries
Sponsor
Sue Barber-Westin
Enrollment
20
Locations
1
Primary Endpoint
Elimination of knee giving-way
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The purpose of this investigation is to determine the clinical outcome of surgical reconstruction of complete ruptures to the posterior cruciate ligament (PCL) and posterolateral structures of the knee joint. The outcome will be determined with validated and rigorous knee rating systems between 2 and 10 years postoperatively. The results will be determined by the analysis of subjective and functional factors, sports and occupational activity levels, a comprehensive physical examination, and a radiographic evaluation. We hypothesize that the appropriately indicated procedures will effectively restore normal knee stability and function in patients with isolated or combined injuries to these structures.

Detailed Description

Because injuries to the PCL and posterolateral structures occur with less frequency than other structures in the knee joint (such as the anterior cruciate ligament and menisci), fewer studies are available to assist the surgeon and patient with appropriate decision-making regarding conservative versus surgical treatment. The majority of patients who sustain injury to these structures are treated conservatively. Unfortunately, several investigations describe noteworthy symptoms and functional limitations following conservative management, and a high percentage of patients develop knee osteoarthritis that can be disabling for both recreational and daily activities. The investigators of this study have nearly three decades of experience and have extensively studied the effects of this injury in both the laboratory and clinic settings. It is our opinion that surgical reconstruction provides significant benefit when appropriately indicated, as has been demonstrated in our previous studies. Especially in athletic individuals, PCL and posterolateral reconstructive procedures have advanced to the point where more predictable results can be expected to restore sufficient knee function. Studies have demonstrated, at least in the short-term, that the majority of patients with acute ligament ruptures treated with reconstruction are able to return to various levels of sports activities.12 Whether these procedures will decrease the risk of the patient developing future osteoarthritis is unknown and requires further study.

Registry
clinicaltrials.gov
Start Date
October 2009
End Date
December 31, 2018
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Sue Barber-Westin
Responsible Party
Sponsor Investigator
Principal Investigator

Sue Barber-Westin

Director Clinical Studies

Cincinnati Sportsmedicine Research and Education Foundation

Eligibility Criteria

Inclusion Criteria

  • Complete rupture to the posterior cruciate ligament, greater than 10 mm of increased posterior tibial translation
  • Rupture to the posterolateral knee structures, greater than 5 mm of increased lateral tibiofemoral joint opening, greater than 10 degrees of increased external tibial rotation
  • Patient willing to comply with postoperative rehabilitation program

Exclusion Criteria

  • Patient unwilling to participate

Outcomes

Primary Outcomes

Elimination of knee giving-way

Time Frame: Minimum 2 years postoperatively

Secondary Outcomes

  • Posterior tibial translation(Minimum 2 years postoperative)
  • Lateral tibiofemoral joint opening(Minimum 2 years postoperatively)
  • External tibial rotation(Minimum 2 years postoperatively)
  • Elimination of knee pain(Minimum 2 years postoperatively)

Study Sites (1)

Loading locations...

Similar Trials