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临床试验/CTRI/2025/09/095026
CTRI/2025/09/095026尚未招募2/3 期

Comparison of ultrasound guided Modified Thoraco-Abdominal nerve block through Perichondrial Approach(M-TAPA) with ultrasound guided Subcostal Transversus Abdominis Plane(TAP) block for postoperative analgesia in patients undergoing laparoscopic cholecystectomy.

Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年9月30日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Total dose of Tramadol consumed (mg) in first 24hours.

研究概览

简要总结

This randomized controlled study aims to compare the efficacy of two regional anesthesia techniques—M-TAPA and subcostal TAP block—in providing postoperative analgesia for patients undergoing laparoscopic cholecystectomy under general anesthesia. While subcostal TAP block is an established technique targeting the T6–T9 dermatomes, its effect on visceral pain is limited. The novel M-TAPA block is believed to provide a broader somatic and potentially visceral blockade (T5–T12) by depositing local anesthetic under the perichondrium of the costal cartilage. The study will evaluate total tramadol consumption in the first 24 hours postoperatively as the primary outcome. Secondary outcomes include pain scores (NRS), time to first rescue analgesic, time taken to perform the blocks, and block-related complications.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • 1.Age 18-65 years 2.Patients of ASA status I and II 3.Patients undergoing Laparoscopic cholecystectomy under general anesthesia.

排除标准

  • 1.Patients allergic to local anaesthetics 2.Pre-existing coagulation disorders 3.Pregnancy 4.BMI greater than 35 kg/m2 5.Previous history of abdominal surgery or trauma.

结局指标

主要结局

Total dose of Tramadol consumed (mg) in first 24hours.

时间窗: 24hours.

次要结局

  • -Time to demand the rescue analgesic (TRAMADOL) in hours.(-NRS Score at rest and coughing at 0,1,3,6,12 and 24.)

研究者

发起方
Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

JYOTI KUMARI

ABVIMS and Dr Ram Manohar Lohia Hospital

研究点 (1)

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