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临床试验/NCT02082106
NCT02082106已完成不适用

Metabolic and Physiological Stress During Alpine Skiing, Cross-country Skiing and Indoor Training in Untrained and Trained Persons.

Paracelsus Medical University1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2014年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
21
试验地点
1
主要终点
Oxygen consumption (VO2)

研究概览

简要总结

Problem description In industrialized countries there is a rapid increase in the number of senior citizens. In Austria more than 50% of the population is overweight, with highest prevalence in the age group from 60 to 74 yrs and the WHO lists physical inactivity as one of the main behavioral risk factors of cardiovascular diseases.

Especially in winter months, activity related energy expenditure was 40% and 31% lower in the US and Canada, respectively. In addition, in an Austrian study the winter season was associated with higher blood pressure, total cholesterol and body mass index, giving an increasing risk of chronic coronary disease by 6.8% in men and 3.6% in women.

Therefore, the development of intervention programs that overcome the winter physical activity deficit and be feasible also for elderly should be goal of future research. Alpine skiing (AS) and cross country skiing (XCS) have a long standing tradition in Austria and could potentially fill the winter physical activity gap. The Salzburg Skiing for the Elderly Study (SASES) has found AS to be a save and feasible possibility to improve the health of the aged population in many parameters. XCS as a competitive sport is already well explored but there are hardly any studies about its effects in the normal or elderly population. Unfortunately knowledge about the differences between AS and XCS in the physiological adaptation processes in the elderly population is also lacking.

Aims and hypotheses of the pre-study In order to standardize training interventions, the present pre-study aims at comparing physiological and metabolic parameters between AS, XCS and IT. Therefore, the results of the pre-study serve as determinants for the training parameters of the above mentioned main study.

We postulate that, based on the results of the present study, it is possible to set up comparable isocaloric training sessions for AS, XCS and IT for elderly and unfit persons.

Furthermore, we assume that elderly and unfit subjects are able to perform a full spectrum of intensities and techniques necessary to set appropriate stimuli for isocaloric comparison.

We hypothesize arterial stiffness indices and circulating microRNA (miRNA) patterns to change due to one bout of physical activity of AS, XCS, and IT with variations depending on the kind of sport.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • written informed consent
  • male or female
  • age: 30+ years
  • inconspicuous ECG
  • Non-smoker for at least one year
  • proper skills in alpine skiing and cross-country skiing

排除标准

  • Participation in other clinical trials at the same time or within the previous 6 months
  • Tiffeneau-Pinelli index: Forced Expiratory Volume in first second (FEV1) / Forced Vital Capacity (FVC) <60% with/without symptoms (coughing, sputum) or other evidence of a pulmonary disease
  • medical condition which conflicts with participation in training
  • Intake of anticoagulants
  • Alcohol or drug abuse
  • Severe obesity: BMI >40

结局指标

主要结局

Oxygen consumption (VO2)

时间窗: 12 weeks

VO2 will be measured during during physical examination, indoor training, Alpine Skiing, and Cross Country Skiing. VO2 will be transformed into metabolic equivalents to calculate isocaloric training parameters for the different kind of sport.

次要结局

  • Pulse wave analysis (PWA)(12 weeks)

研究者

发起方
Paracelsus Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Prof. Josef Niebauer M.D., Ph.D., MBA

Head of Institute; University Institute of Sports Medicine, Prevention and Rehabilitation

Paracelsus Medical University

研究点 (1)

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