Sonographic Parameters and Risk of Antepartum Hemorrhage in Asymptomatic Women With Placenta Previa: A Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- maternal bleeding rate
研究概览
简要总结
The aim of this study is to evaluate the effectiveness of ultrasonographic parameters (cervical length, placental thickness and distance placental edge from internal os of the cervix) in predicting the risk of antepartum hemorrhage and emergency cesarean delivery in asymptomatic women with placenta previa.
详细描述
The incidence of placenta previa is 3-5 per 1000 pregnancies worldwide and is still rising because of increased maternal age, parity, cesarean section rates, assisted reproductive technology, maternal smoking with the widespread use of transvaginal ultrasound. antepartum hemorrhage is an important cause of maternal and neonatal morbidity and mortality in pregnant women with placenta previa. However, the epidemiological characteristics are not completely understood. this study aims at evaluating the sonographic findings in asymptomatic women with placenta previa as cervical length, placenta thickness and distance from cervix to placental edge to recommend management for in-patients versus out-patient antenatal care and early planned hospital admission and delivery for women at high risk of antepartum hemorrhage and preterm cesarean section and hysterectomy for life threatening antepartum hemorrhage.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Asymptomatic women diagnosed with placenta previa according to RCOG (GTG No. 27a, 2018): placenta lies directly over the internal os for pregnancies more than 16 weeks' gestation on transabdominal or transvaginal scanning.
- •Gestational age between 28 till 37 weeks' gestation (as delivery should be considered between 36 and 37 weeks of gestation for women presenting with uncomplicated placenta previa)
排除标准
- •Multiple pregnancies.
- •Threatened preterm labor or preterm rupture of membranes.
- •History of bleeding in the current pregnancy.
- •Polyhydraminos (AFI > 25 cm).
- •History of cervical surgery (cone biopsy).
- •Presence of cervical cerclage.
- •Maternal use of vaginla progesterone.
- •History of maternal disease (hypertensive, DM, Cardiac).
- •Fetal malformation or growth restriction
结局指标
主要结局
maternal bleeding rate
时间窗: till delivery
number of attacks of antepartum hemorrhage
次要结局
- Emergency Cesarean section(till delivery 36 to 37 weeks)
- Blood transfusion(till delivery 36 to 37 weeks)
- Premature delivery(37 week's gestation)
- Postpartum hemorrhage(Within 2 hours of delivery)
- Need for cesarean hysterectomy(during cesarean section)
研究者
Maya Abdelrazek
Lecturer
Ain Shams University