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Clinical Trials/NCT04787172
NCT04787172
Unknown
Not Applicable

Role of the Multi-Slice Computed Tomography in Evaluation of the Congenital Cardiovascular Anomalies

Assiut University0 sites50 target enrollmentJune 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
MSCT in Congenital Cardiovascular Disease
Sponsor
Assiut University
Enrollment
50
Primary Endpoint
accuracy of the MSCT in congenital cardiovascular anomalies
Last Updated
5 years ago

Overview

Brief Summary

Congenital heart diseases (CHDs) are considered as the most common congenital birth defects, comprising 1% of all live births . Echocardiography remains a first-line non-invasive imaging tool for establishing the diagnosis and follow-up in most patients .This method is operator dependent and limited by an acoustic window .

Traditional angiography is typically utilized as the gold standard modality for diagnosing CHD, but it is an invasive method and need general anseathsia with dose of radiation exposure .After recent developments in CT and MR technologies, cardiac catheterization is no longer necessary for diagnosis .

Detailed Description

The interpretation of cardiovascular structures on cardiac CT scan studies is similar to that for echocardiography, however, it is not limited by the acoustic window or operator dependent like ultrasonography. In addition to the anatomic information, a cardiac CT scan provides hemodynamic information, including extracardiac and intra-cardiac shunts. It also enables the systematic evaluation of other thoracic structures like cardiovascular structures, the airways and the lungs by using maximum and minimum intensity projections to delineate the vascular and airway structures, respectively. Extra-cardiac great vessels can be evaluated along their length; thus augmenting the role of cardiac CT scans in children with congenital heart diseases .Inspite of the poorer temporal resolution of cardiac CTA compared to echocardiography, yet the combination of rapid acquisition time, increased anatomic coverage, high spatial resolution, multiplanar reformation and 3D capability combined with a flexible ECG synchronization have improved the image quality of cardiac CT scans and minimizing the patient risks. Multidetector computed tomography has greatly advanced the noninvasive diagnosis of these anomalies in pediatric patient, thus makes MDCT an ideal non- invasive method for evaluating pediatric patients .

Registry
clinicaltrials.gov
Start Date
June 1, 2021
End Date
September 1, 2022
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sara Ali Gamal

specialist

Assiut University

Eligibility Criteria

Inclusion Criteria

  • patients suffering from congenital cardiovascular diseases diagnosed either clinically or by echocardiographic examination.

Exclusion Criteria

  • orthopenic patient patients with hypersensitivity to contrast , medium and poor renal function .

Outcomes

Primary Outcomes

accuracy of the MSCT in congenital cardiovascular anomalies

Time Frame: baseline

comparison between sensitivity and accuracy of MSCT in detection of congenital cardiovascular anomalies with detection rate by cardiac catheterization or surgery

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