The effect of mefenamic acid, naproxen and placebo on periodic bleeding in wome
- Conditions
- Heavy menstrual bleeding.Excessive and frequent menstruation with irregular cycle
- Registration Number
- IRCT201204241548N14
- Lead Sponsor
- Deputy for Research of Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 120
Inclusion criteria were the followings: a) being between 20 and 45 years old of age; b) normal ?results for cervical smear test; c) negative history of renal or hepatic impairment, ?thromboembolic disease, inflammatory bowel disease, peptic or intestinal ulceration, ?coagulation or fibrinolytic disorders; d) normal results for blood tests (including PT, PTT, BT, ?TSH); e) not taking any hormones and NSAIDS.?
Exclusion criteria included: a) infertility; b) overweight/obesity (BMI>25) or underweight ??(BMI<18.5); c) polycystic ovaries; d) vaginitis and/or pelvic inflammatory disease (PID); e) ?uterine polyps and/or fibroids; f) carrying IUD; g) being perimenopausal (increased serum ?FSH showed being premenopausal). ?
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of menstrual bleeding. Timepoint: One month. Method of measurement: Pictorial Blood Assessment Chart ?.
- Secondary Outcome Measures
Name Time Method Decrease in the amount of menstrual bleeding. Timepoint: one month. Method of measurement: Pictorial Blood Assessment Chart ?.