Effect of treatment using Takra in the management of Grahani Dosha (Irritable bowel syndrome)

Phase 2

Completed

• Conditions: Health Condition 1: K582- Mixed irritable bowel syndrome

• Registration Number: CTRI/2021/01/030781
• Lead Sponsor: All India Institute of Ayurveda

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 March 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients irrespective of sex, religion, occupation will be selected for study.

2. Patients having pratyatma lakshana of Grahani Dosha especially – Atisrushtam or Ativibadhham or Atidravam malapravritti (altered bowel

habits), Trushna, Arochaaka, Vairasya, Praseka, Tamaka, Shoona pada,

Shoona kara, Asthi-parva ruja, Chhardi, Jwara, Louha-ama-gandhi

tiktamlodgara.

3. The patients who are diagnosed with IBS according to standard ROME IV criteria.

4. Previously diagnosed case of IBS.

5. Able and willing to give written informed consent.

Exclusion Criteria

Mixed infection with parasites such as round worms, hook worms etc.

1. Ulcerative colitis, Crohn’s disease, gastric ulcerations and other inflammatory

bowel conditions.

2. Infectious disorders like Intestinal tuberculosis etc.

3. Patients with evidence of malignancy.

4. Patents with diabetes mellitus (FBS >126 mg/dl, PP >200 mg/dl), poorly

controlled hypertension, Thyroid disorders and any other autoimmune disorders.

5. Amoebic dysentery, acute diarrhoea.

6. Lactose intolerance patients.

7. Abuse of drug or alcohol.

8. Presence of other somatic or mental disorder requiring medication.

9. Patients on prolonged medication with NSAIDs, analgesics or any other drugs

that may have an influence on the outcome of the study.

10. History of hypersensitivity to any of the trial drugs or their ingredients.

11. Patients who have completed participation in any other clinical trial during the

past 6 months which is interfering with the results of Grahani Dosha.

12. Patients with bleeding per rectum.

13. All the types of atisara, Antraja krimija patients and any other conditions

interfering with the results of Grahani Dosha / IBS.

Study & Design

• Study Type: Interventional
• Study Design: Not specified