Efficacy and safety of Topical Tofacitinib in hand eczema A quasi experimental single armed study
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To find out the efficacy of topical tofacitinib in treatment of chronic hand eczema
研究概览
简要总结
This is a quasi-experimental single armed study to asses the safety and efficacy of topical tofacitinib in chronic hand eczema .All the patient recruited after meeting the inclusion criteria detailed history including duration of disease ,history of atopy treatment history will be taken. All the patient will be given Topical Tofacitinib to apply along with bland emollient and antihistaminic .patient will be asked to follow up first in 2nd week then again finally in 4th week .Hand eczema severity score will be calculated at the baseline again in 2nd and 4th week .Clinical photographs will be taken in every visit .Dermatologically life quality index will be recorded at base line and at the 4th week .
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •patients of hand eczema diagnosed clinically or histopathologically hand eczema lasting for more than or equal to 3 months or with two episodes per year age more than 18 years.
排除标准
- •preganancy and lactation very severe hand eczema( hand eczema severity index score more than 117) patient on concurrent systemic immunosuppressive or with in last 4 weeks patient on concurrent topical immunomodulators/immunosuppressants or within last 4 weeks.
结局指标
主要结局
To find out the efficacy of topical tofacitinib in treatment of chronic hand eczema
时间窗: Base line second week fourth week
次要结局
- To assess the safety of topical tofacitinib in treatment of chronic hand eczema(1 month)
研究者
DR TANISHA NAYAK
IMS & SUM HOSPITAL BHUBANESWAR