Endoscopic Submucosal Injection of Indocyanine Green Before Laparoscopic Radical Resection for Colorectal Cancer

• Conditions: Colorectal Cancer; Indocyanine Green
• Interventions: Procedure: endoscopic submucosal injection of indocyanine green before laparoscopic radical operation of colorectal cancer

• Registration Number: NCT04207489
• Lead Sponsor: Jilin University

Brief Summary

Prospective registry study of endoscopic submucosal injection of indocyanine green before laparoscopic radical resection for colorectal cancer

Detailed Description

To observe the imaging result of endoscopic submucosal injection of indocyanine green before laparoscopic radical resection for colorectal cancer, and analyze the relevant factors, so as to guide the submucosal injection of preoperative indocyanine green better.

This study is prospective and observational. In order to analyze the related factors that affect the imaging effect, we enrolled patients who were to undergo indocyanine green fluorescence imaging for laparoscopic radical resection for colorectal cancer.

Study Timeline

• Study First Submitted: 2019-12-17
• Study First Submitted QC: 2019-12-17
• Study First Posted: 2019-12-23
• Study Start: 2020-04-15
• Status Verified: 2020-08
• Last Update Submitted: 2020-08-20
• Last Update Posted: 2020-08-24
• Primary Completion: 2020-12-25
• Study Completion: 2021-04-28

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients who were to undergo indocyanine green fluorescence imaging for laparoscopic radical operation of colorectal cancer.

Exclusion Criteria

• have simultaneously other cancer

  • have severe systemic inflammatory disease ,serious illness such as diabetes, chronic lung diseases
  • have gastrointestinal surgery
  • Indocyanine green or iodine allergy
  • the period is too late or the tumor is too large to carry on a laparoscopic surgery.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
endoscopic submucosal injection of indocyanine green	endoscopic submucosal injection of indocyanine green before laparoscopic radical operation of colorectal cancer	-

Primary Outcome Measures

Name	Time	Method
The imaging effect of indocyanine green	During the operation	The imaging effect was evaluated by indocyanine green fluorescence imaging system during the operation. According to the imaging effect, it can be divided into local imaging and lymphatic drainage imaging. Tumor body: 0, no imaging; 1, full imaging; 2, diffuse imaging, overflow, interference with other areas of observation. Lymph drainage area imaging 0, no imaging; 1, full imaging; 2, diffuse imaging, overflow, interference with other areas of observation.

Trial Locations

Locations (1)

the First Hospital of Jilin University; 🇨🇳 Chang chun, Ji Lin, China