Erectile Dysfunction in Severe Obstructive Sleep Apnea: Effects of CPAP Therapy

Completed

• Conditions: Obstructive Sleep Apnea; Erectile Dysfunction

• Registration Number: NCT01600066
• Lead Sponsor: University of Giessen

Brief Summary

Obstructive sleep apnea has been linked to erectile dysfunction. Furthermore, small studies suggest that treatment of sleep apnea by continuous positive airway pressure (CPAP) may reverse erectile dysfunction in affected patients. The present study aims to investigate in a larger cohort if severe sleep apnea is independently associated with erectile dysfunction and if 6-12 months of CPAP therapy lead to an improvement of erectile dysfunction.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05
• Study First Submitted: 2012-05-09
• Study First Submitted QC: 2012-05-14
• Study First Posted: 2012-05-16
• Status Verified: 2015-12
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Last Update Submitted: 2015-12-02
• Last Update Posted: 2015-12-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 200

Inclusion Criteria

• apnea-hypopnea-index > 30/h
• no CPAP therapy
• male gender
• 18-80 years of age
• having or attempting to have regular sexual intercourse

Exclusion Criteria

• apnea-hypopnea-index < 30/h
• already treated by CPAP
• female gender
• age < 18 or > 80 years
• not having or not attempting to have regular sexual intercourse

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of erectile function in severe sleep apnea after 6-12 months of CPAP therapy	at the time of diagnosis of sleep apnea and after 6-12 months of CPAP therapy	an established self-administered questionnaire is used to assess changes in erectile function occurring after 6-12 months of CPAP therapy in patients with severe sleep apnea