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Effects of interval exercise training on MirRNA levels in breast cancer

Phase 2
Conditions
Breast cancer.
Breast, unspecified
Registration Number
IRCT2014081018745N1
Lead Sponsor
Vice-?hancellor for Research of Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
64
Inclusion Criteria

Randomize; obtaining informed consent; patients with non-metastatic disease (level 1 to 3); completed treatment with chemotherapy and radiotherapy (at least one month); patients with estrogen and progesterone receptors.
Exclusion criteria: patients with tobacco and alcohol consumption; patients with unwillingness to exercise; patients with serious acute and chronic heart failure; patients with serious chronic respiratory failure; patients with chronic liver failure; patients with metastatic disease to bone and brain.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Serum level of miR-21. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-222. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-155. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-let7. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-143. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-145. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-206. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-221. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.;Serum level of miR-200. Timepoint: Before and after of exercise. Method of measurement: QPCR-Real Ttime.
Secondary Outcome Measures
NameTimeMethod
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