The Link Between the Clinical Resting Heart Rate and Sympathetic Overactivation

• Conditions: Cardiovascular Disease

• Registration Number: NCT02315313
• Lead Sponsor: Ruijin Hospital

Brief Summary

It is a retrospective study with no products limitation to investigate the link between clinical resting HR and SOA. Use HR≤60bpm as control group, compare other three groups with the control group and find out the correlation between HR and SOA indexes.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-12
• Study Start: 2014-12
• Study First Submitted: 2014-12-02
• Study First Submitted QC: 2014-12-08
• Last Update Submitted: 2014-12-08
• Study First Posted: 2014-12-11
• Last Update Posted: 2014-12-11
• Primary Completion: 2015-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1. Provision of subject informed written or oral consent
2. Female and male aged≥ 20 to ≤ 80 years;
3. Records on mean clinical heart rate and SOA indexes were available.

Exclusion Criteria

1. Participation in another clinical study with an investigational product during the last 6 months;
2. Drug intervention on heart rate 1 month prior to the inclusion;
3. Patients with missing data in the database from the Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The difference of HRV, BPV, LF/HF between each groups	1min HR measure	The difference on mean sympathetic overactivation related indexes such as HRV, BPV, LF/HF between groups