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Clinical Trials/NCT06736964
NCT06736964
Enrolling By Invitation
Not Applicable

Clinical Evaluation of Different Bioactive Restorative Materials for Cervical Carious in High Caries Risk Patients :A Randomized Clinical Trial

Cairo University1 site in 1 country30 target enrollmentOctober 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Class V Dental Caries
Sponsor
Cairo University
Enrollment
30
Locations
1
Primary Endpoint
clinical performance (Post operative hyper sensitivity)
Status
Enrolling By Invitation
Last Updated
last year

Overview

Brief Summary

The aim of the study is to clinically evaluate three different bioactive restorative material in cervical carious lesion in high caries risk patients.

Reducing the incidence of recurrent caries is the primary outcome

Detailed Description

Bioactive restorative materials are relatively new concept in dentistry combines between esthetics, strength and resilience of composites with bioactive properties, the development of therapeutic bio-interactive materials results in tissue re-mineralization, reduces the susceptibility to tooth mineral loss, and recovers its mechanical properties . Patients, with high caries, have many risk factors like inadequate biofilm control, salivary flow deficiency, and altered host defense. Conventional restorative materials expose the tooth structure to stress concentration. Moreover, preserving the tooth restoration interface intact is great challenge to avoid recurrent caries, which may also result in restoration failures . This prospective study will be investigating and comparing the eighteen month clinical performance of a different bioactive restorative materials and a conventional Pre-reacted glass ionomer restorative material in class V cavity preparation.

Registry
clinicaltrials.gov
Start Date
October 1, 2024
End Date
April 1, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yehia Hafez Yehia

Lecturer of Conservative Dentistry Department

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Patient age range from 25-45 year.
  • High risk caries.
  • Patients required at least a couple of Class V restorations.
  • The depth of lesion should be(1.5- 2 mm) .
  • The patient should have good general health

Exclusion Criteria

  • Poor oral hygiene.
  • Sever or chronic periodontal disease or Bruxism.
  • Severe tooth sensitivity.
  • Non-vital or fracture or cracked teeth.
  • Defective restorations, orthodontic treatment or bleaching procedures during the last 6 months.
  • pregnancy, and/or lactation, and allergy to the main components of the products to be used in the study

Outcomes

Primary Outcomes

clinical performance (Post operative hyper sensitivity)

Time Frame: 12 months

method of measurement is Modified United State Public Health Service Criteria (Modified USPHS) using Binary (yes/ no) yes outcome mean recurrent caries present, no mean no recurrent caries present .

Secondary Outcomes

  • clinical performance (Fracture and retention, marginal integrity, marginal discoloration, anatomic form, surface texture, postoperative sensitivity)(18 months)

Study Sites (1)

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