Can Intermittent Fasting Mimic the Metabolic and Cardiovascular and Anti-aging Effects of Calorie Restriction?

Not Applicable

Completed

• Conditions: Obesity; Overweight

• Registration Number: NCT01964118
• Lead Sponsor: Washington University School of Medicine

Brief Summary

The purpose of Intermittent Fasting study is to investigate whether intermittent fasting could decrease the chronic inflammation levels in overweight/obese people.

Detailed Description

The primary objective of this study is to determine whether or not IF reduces the level of chronic inflammation as evidenced by a decrease in high sensitive C-reactive protein (hsCRP), as the main outcome measure

Study Timeline

• Study Start: 2013-07
• Study First Submitted: 2013-10-07
• Study First Submitted QC: 2013-10-14
• Study First Posted: 2013-10-17
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Status Verified: 2021-05
• Last Update Submitted: 2021-05-21
• Last Update Posted: 2021-05-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• The participants in this study will be 50 men and women in the 30 to 65 year age range, who have a BMI in the high normal to moderately obese range (i.e. 24 to 35 kg/m2),
• Participants who are eating usual US diets and are sedentary to moderately active (i.e. not exercise trained).

Exclusion Criteria

• History of any chronic disease process that could interfere with interpretation of results
• Smoking, pregnancy, alcoholism, psychiatric problems, life situations that would interfere with study participation and compliance.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Change in HSCRP ( high sensitivity C-reactive protein) at 6 and 12 months	Every 6 months- baseline, 6 month and 12 month	HSCRP would be measured in mg/L

Trial Locations

Locations (1)

Washington University School of Medicine; 🇺🇸 Saint Louis, Missouri, United States