Biological and clinical effect of antimicrobial photo dynamic therapy and local drug delivery system for chronic periodontitis: a randomized controlled clinical trial
Not Applicable
- Conditions
- Chronic periodontitis
- Registration Number
- JPRN-UMIN000013376
- Lead Sponsor
- iigata University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1. Persons who had received scaling and root planing within the previous 3 months 2. Persons who had taken systemic antibiotics or anti-inflammatory drugs within 3 months before experiment 3. Persons who had severe systemic diseases 4. Persons who is known or suspected hypersensitivity or intolerance to tetracyclines antibiotics, chlorhexidine and methylene blue. 5. Smoker 6. Persons who is suspected of having aggressive periodontitis 7. Persons who are pregnant or suspected to be pregnant. 8. Persons who have acatalasia, severe G6PD deficiency, Photosensitive epilepsy. 9. Persons who are judged to be unqualified for this study subjects by investigators.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of total bacteria and some periodontopathic bacteria in subgingival plaque
- Secondary Outcome Measures
Name Time Method *Probing pocket depth *Bleeding on probing *Profile of bacterial flora in subgingival plaque *Biomarker level in gingival crevicular fluid