ISRCTN05745813已完成不适用
Phase III trial in patients with multiple myeloma to optimize bortezomib based induction (bortezomib, Adriamycin®, dexamethasone [PAd] vs. bortezomib, cyclophosphamide, dexamethasone [VCD]) prior to high dose therapy and autologous stem cell transplantation followed by lenalidomide based consolidation and maintenance therapy
Heidelberg University (Germany)0 个研究点目标入组 504 人开始时间: 2009年11月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 504
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Confirmed diagnosis of multiple myeloma requiring systemic therapy
- •2. Measurable disease
- •3. Age 18 - 70 years inclusive, either sex
排除标准
- •1. Previous chemotherapy or radiotherapy during the past 5 years except local radiotherapy in case of local myeloma progression
- •2. Severe cardiac dysfunction
- •3. Significant hepatic dysfunction
- •4. Patients known to be human immunodeficiency virus (HIV)-positive
- •5. Patients with active, uncontrolled infections
- •6. Patients with peripheral neuropathy or neuropathic pain, Common Toxicity Criteria (CTC) grade 2 or higher
- •7. Patients with a history of active malignancy during the past 5 years
- •8. Systemic AL amyloidosis
研究者
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