Qudratus Lumborum Block Versus Unilateral Intrathecal Block for Inguinal Hernia Repair

Not Applicable

• Conditions: Inguinal Hernia,Quadratus Lumborum Block , Unilateral Intrathecal Block
• Interventions: Procedure: unilateral intrathecal block

• Registration Number: NCT04805580
• Lead Sponsor: Zagazig University

Brief Summary

compare between Quadratus lumborum block and unilateral intrathecal block for patients undergoing inguinal hernia repair regarding the quality of anesthesia and hemodynamic stability of patients.

Detailed Description

comparison between unilateral intrathecal block anesthesia (unilateral SA) and Quadratus lumborum block for inguinal hernia repair unilateral intrathecal block is widely used nowadays for unilateral inguinal hernia repair, providing intense sensory and motor blockade. Limiting the block to the operative site by using small doses of hyperbaric solutions injected slowly through a directional needle and maintaining a lateral decubitus position for a certain duration has been proposed, to produce high quality, long-duration analgesia, with minimal hemodynamic adverse events.

Previous case report studies stated that we can use Quadratus Lumborum Block as the sole anesthetic technique for open hernia repair.

Study Timeline

• Study First Submitted: 2021-03-15
• Study First Submitted QC: 2021-03-15
• Study First Posted: 2021-03-18
• Status Verified: 2021-04
• Last Update Submitted: 2021-04-05
• Last Update Posted: 2021-04-06
• Study Start: 2021-05
• Primary Completion: 2021-09
• Study Completion: 2021-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• physical status ASA: I-II BMI >18kg/m2<30kg/m2 written informed consent from the patient scheduled for open unilateral inguinal hernia repair

Exclusion Criteria

• uncooperative patient
• Allergy to local anesthetic drugs
• patients on chronic alcohol, opioid, tranquilizer or sedative use
• Pregnant females.
• Psychological, mental disorders, or depression.
• Patients receiving anticoagulants therapy or suspected coagulopathy.
• Patients with infection or previous surgery at sit of anesthetic procedures.
• Patients with significant cardiovascular, respiratory, renal, hepatic, or metabolic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
intrathecal block	unilateral intrathecal block	patients (25) will receive unilateral intrathecal block using 1.5 ml of hyperbaric bupivacaine
Quadratus lumborum block	unilateral intrathecal block	patients (25) will receive quadratus lumborum block by an anterior approach using 30 ml of bupivacaine 0.25%

Primary Outcome Measures

Name	Time	Method
To assess safety of quadratus lumborum block vs unilateral intrathecal block for inguinal hernia repair: complications of the block	2 hours	complications of the block in each group like inadequate blockade detected by increased dose of sedation required in this group ,hemodynamic instability related to the block detected by frequent monitoring of the blood pressure and heart rate

Secondary Outcome Measures

Name	Time	Method
To compare the onset and duration of sensory block between both blocks	12 hours	the onset of pin brick discrimination and time of first request of analgesics after block performance in each group
To compare the time to ambulation	24 hours	the time till the patient succeed in ambulation