the efficacy of topical erythropoietin treatment on healing of second degree burned cutaneous burned wounds

Phase 3

Conditions: Burn.
Other disorders of skin and subcutaneous tissue in diseases classified elsewhere

Registration Number: IRCT20190810044500N23

Lead Sponsor: Yazd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 48

Inclusion Criteria

Presenting to the burn center in the first 24 hours after the burn
Having grade II burns, superficial and deep, that involve less than 10% of the body's surface area
No comorbidity that delays the repair process (such as diabetes, chronic kidney disease, malignancy, and chronic use of corticosteroids)
Absence of respiratory burns as well as chemicals or electric burn
No burns on the face and perineum and hand

Exclusion Criteria

Concurrent infection during the study
Lack of response to treatment
The need for skin graft surgery

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean time of wound healing. Timepoint: The wound healing process is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Erythropoietin cream on the wound area. Method of measurement: Clinical examination.;The rate of pigmentation. Timepoint: The rate of pigmentation is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Erythropoietin cream in the wound area. Method of measurement: Clinical examination.;The rate of pain. Timepoint: The rate of pain is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Erythropoietin cream in the wound area. Method of measurement: Clinical examination.;The rate of pruritus. Timepoint: The rate of pruritus is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Erythropoietin cream in the wound area. Method of measurement: Clinical examination.

Secondary Outcome Measures