Reward Sensitivity and Stress Vulnerability: A pilot study.

• Conditions: Reward sensitivity.Stress vulnerability.Healthy volunteers.

• Registration Number: NL-OMON28401
• Lead Sponsor: Maastricht University

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

1. Aged between 18 – 35;

2. Sufficient command of the Dutch language to understand and give informed consent;

Exclusion Criteria

1. Current Axis I diagnosis of psychiatric disorder or personality disorder;

2. Current alcohol or substance abuse;

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In the reward-learning paradigm, the main study parameter is the performance on the computerized task as measured by percentage correct choices of the rewarding stimulus relative to the losing stimuli. <br /><br>In both the ostracism and the social stress paradigms, the main study parameter is the change in stress scores endorsed by the participants on behavioural questionnaires, as a function of exposure to stressful stimuli. A parallel study parameter is the change in salivary cortisol concentrations as a function of exposure to the stress manipulation.

Secondary Outcome Measures

Name	Time	Method
An additional study parameter is the change of stress scores from baseline (baseline) to multiple endpoints (immediately post-study, few hours post-study, the next day, etc) within each individual subject.