Ultra-Widefield Fluorescein Angiography-Based Targeted Retinal Photocoagulation Versus Conventional Panretinal Photocoagulation in the Preservation of Visual Function and Regression of Proliferative Diabetic Retinopathy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- CMT
研究概览
简要总结
Proliferative diabetic retinopathy is a vision-threatening disease that can lead to irreversible visual loss. The treatment options for proliferative diabetic retinopathy are anti-VEGF injection and retinal photocoagulation. The study aims to compare ultra-widefield fluorescein angiography-based targeted retinal photocoagulation and panretinal photocoagulation in the treatment of proliferative diabetic retinopathy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •proliferative diabetic retinopathy (PDR) with neovascularization on the disc or elsewhere in the retina
排除标准
- •Participants with a history of previous history of:
- •retinal photocoagulation
- •vitreoretinal surgery
- •tractional retinal detachment
- •epiretinal membrane
- •vitreomacular traction
- •media opacities like cataract, corneal opacity, vitreous hemorrhage
- •anti-VEGF injections in last 3 months
研究组 & 干预措施
TRP
Targeted Retinal Photocoagulation
干预措施: Green laser (Procedure)
PRP
Panretinal Photocoagulation
干预措施: Green laser (Procedure)
结局指标
主要结局
CMT
时间窗: 2 months
Central Macular Thickness
MD
时间窗: 2 months
Mean Deviation
VFI
时间窗: 2 months
Visual Filed Index
BCVA
时间窗: 2 months
Best Corrected Visual Acuity
次要结局
未报告次要终点
研究者
Yousaf Jamal Mahsood
Associate Professor
Hayatabad Medical Complex