DOSIMETRIC BENEFIT OF DEEP INSPIRATION BREATH-HOLD TECHNIQUE FOR PATIENTS WITH LEFT BREAST CANCER RECEIVING RADIATION POST MASTECTOMY
Phase 2
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2021/09/036178
- Lead Sponsor
- DEPARTMENT OF RADIOTHERAPY
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Histologically proven cases of left sided breast carcinoma after mastectomy with or without lymph node positivity planned for DIBH-RT.
2. Karnofskyâ??s performance scale score (KPS) greater than or equal to 70
Exclusion Criteria
1.Patients with BCS
2.Right sided breast carcinoma
3.Metastatic disease
4.KPS score <70
5.Patients with medical history of active cardiac diseases like arrhythmias, myocardial infarction, and congestive heart failure.
6.Inability to establish a reproducible breathing pattern.
7.Inability to maintain breath holding for 20secs at least due to compromised lung function.
8.Need for sedation.
9.Patients with flap reconstruction.
10.Patient refusal.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the following parameters in patients undergoing radiation therapy by DIBH with FB technique. <br/ ><br>1.Mean heart dose <br/ ><br>2.Maximum heart dose <br/ ><br>3.Mean LAD dose <br/ ><br>4.Maximum LAD dose <br/ ><br>5.Mean ipsilateral lung dose <br/ ><br>6.Heart-chest wall separation <br/ ><br>7.V5 heart <br/ ><br>8.V25 heart <br/ ><br>9.V5 ipsilateral lung <br/ ><br>10.V20 ipsilateral lung <br/ ><br>11.Mean contralateral breast dose <br/ ><br>12.Mean contralateral lung dose <br/ ><br>13.V2 contralateral lung <br/ ><br>14.V5 contralateral lung <br/ ><br>Timepoint: After treatment planning.
- Secondary Outcome Measures
Name Time Method nilTimepoint: nil