Effect of Early Analgesic Treatment on Opioid Consumption
Overview
- Phase
- Not Applicable
- Intervention
- Placebo Oral Tablet
- Conditions
- Acute Pain
- Sponsor
- University of Monastir
- Enrollment
- 1500
- Primary Endpoint
- use of rescue opioids
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
introduction: Pain remains one of the most common reasons of emergency department admission. Opioids are overprescribed in emergency departments to treat severe pain.
objective: assessing the impact of ealy pain pain management on the use of intravenous morphine and on patient satisfaction.
Investigators
Pr. Semir Nouira
professor
University of Monastir
Eligibility Criteria
Inclusion Criteria
- •over 18 years of age
- •a visual analog scale (VAS) equal to or higher than 30/100 ,
- •having given consent to participation
- •No contraindications to products used in the course of the study.
Exclusion Criteria
- •having a vital distress that does not allow an adequate assessment of the intensity of the pain
- •an inability to assess pain intensity according to the VAS,
- •swallowing disorders or inability , or a contraindication or an allergy to the treatments used.
Arms & Interventions
group Placebo
Patients in this group (Placebo Oral Tablet) received two placebo tablets
Intervention: Placebo Oral Tablet
group Paracetamol
Patients in this group received two 500 mg paracetamol tablets
Intervention: Paracetamol
group Tramadol/Paracetamol combination
Patients in this group (Tramadol/Paracetamol combination ) received 2 tablets of Tramadol/Paracetamol combination (37.5mg/325mg)
Intervention: Tramadol/Paracetamol combination
Outcomes
Primary Outcomes
use of rescue opioids
Time Frame: DURING emergency department stay
decreased consumption of intravenous morphine
Secondary Outcomes
- patient satisfaction(When quitting emergency department)
- Length of emergency department stay(Until emergency department discharge)
- Pain intensity at emergency department discharge(At emergency department discharge)