Validation of the diffusion MRI signal in kidney tumours: a pilot study

Completed

• Conditions: kidney tumour; Renal Cell Carcinoma; 10038364

• Registration Number: NL-OMON43829
• Lead Sponsor: niversiteit Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

* Volunteers are healthy
* Volunteers and subjects are 18 year or older.
* Volunteers and subjects are capable and prepared to sign an informed consent.
* Subjects are eligible for radical nephrectomy
* Subjects are planned to undergo nephrectomy

Exclusion Criteria

* Subjects and volunteers with contra-indications for MRI (like a pacemaker, claustrophobia).
* Subjects and volunteers with large (known) deviation in kidney anatomy (like horseshoe kidney).
* Refusal of volunteers and subjects to be informed of chance findings possibly relevant to their health.
* Subjects and volunteers with kidney pathologies (other than kidney tumor)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are diffusion MRI derived parameters: FA, MD,<br /><br>pseudodiffusion coefficients and perfusion fractions, that will be correlated<br /><br>with the histological kidney cancer type (clear cell, chromophobe, cystic and<br /><br>papillary renal cell carcinoma).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>na.</p><br>