Monitoring Brain Waves in Response to Visual and/or Auditory Stimulation in Parkinson's Disease Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 主要终点
- Voltage fluctuation resulting from brain activity after auditory stimuli
研究概览
简要总结
Voltage fluctuation as a result of brain activity will be recorded into the computer using an EEG device.
详细描述
Patients with Parkinson's disease may have gait disturbances including freezing of gait. Visual and auditory stimuli may improve gait. Investigators will analyze brain wave during walking while giving the subject different stimuli.
The voltage fluctuation (in hundreds of microvolts) will be recorded using the EEG cap and amplifier into a computer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Parkinson's disease that are ambulatory and can sign a written informed consent
排除标准
- •Patients with Parkinson's disease who are not ambulatory
- •Patients with dementia
- •Patients that are blind
- •Patients that have severe hearing impairment
研究组 & 干预措施
Auditory stimuli
Patients will walk naturally with EEG measuring brain waves while hearing an auditory stimuli
干预措施: Baseline (Behavioral)
Auditory stimuli
Patients will walk naturally with EEG measuring brain waves while hearing an auditory stimuli
干预措施: Auditory stimuli (Behavioral)
Baseline
Patients will walk naturally with EEG measuring brain waves
Visual stimuli
Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses
干预措施: Baseline (Behavioral)
Visual stimuli
Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses
干预措施: visual stimuli (Behavioral)
Visual and auditory stimuli
Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses and hearing an auditory stimuli simultaneously
干预措施: Baseline (Behavioral)
Visual and auditory stimuli
Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses and hearing an auditory stimuli simultaneously
干预措施: Visual and auditory stimuli (Behavioral)
结局指标
主要结局
Voltage fluctuation resulting from brain activity after auditory stimuli
时间窗: One hour
Change in brain wave activity after auditory stimuli as compared with baseline measured in tens of micro-volts per second.
Voltage fluctuation resulting from brain activity after visual and auditory stimuli
时间窗: One hour
Change in brain wave activity after visual and auditory stimuli as compared with baseline measured in tens of micro-volts per second.
Voltage fluctuation resulting from brain activity after visual stimuli
时间窗: One hour
Change in brain wave activity after visual stimuli as compared with baseline measured in tens of micro-volts per second.
次要结局
未报告次要终点