MAGIC Cell-5-Combicytokine Trial

Phase 2

• Conditions: Acute Myocardial Infarction

• Registration Number: NCT00501917
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Combination use of darbepoetin and G-CSF will improve left ventricular systolic function in patients with acute myocardial infarction who receive intracoronary infusion of mobilized peripheral blood stem cell in comparison with patient who treated with conventional measures and who received intracoronary infusion of mobilized peripheral blood stem cell by G-CSF alone.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-03
• Status Verified: 2007-07
• Study First Submitted: 2007-07-13
• Study First Submitted QC: 2007-07-13
• Last Update Submitted: 2007-07-13
• Study First Posted: 2007-07-16
• Last Update Posted: 2007-07-16
• Study Completion: 2010-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• ST elevation acute myocardial infarction
• < 80years
• successful revascularization of culprit vessel

Exclusion Criteria

• uncontrolled congestive heart failure
• uncontrolled myocardial ischemia
• uncontrolled ventricular arrhythmia
• malignancy
• serious hematologic disease
• chronic renal failure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
change of left ventricular ejection fraction measured by cardiac MRI	6, 12, and 24month

Secondary Outcome Measures

Name	Time	Method
wall motion score index exercise capacity BNP	6,12, 24month

Trial Locations

Locations (1)

Seoul National Univesity Hospital; 🇰🇷 Seoul, Korea, Republic of