ACTRN12621000104853已完成3 期
A randomised double-blind placebo-controlled study to evaluate the effect ofcurcumin on BDNF levels in otherwise healthy adults.
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 69
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 40 Years（—）
- 性别
- All
入选标准
- •Male and females aged 18-40 years old
- •Able to provide informed consent
- •Agree not to take other supplements (e.g. curcumin, iron, resveratrol, fish oil) that may affect BDNF for the duration of the trial and within 2 weeks prior to commencing the study
排除标准
- •Iron deficient anaemia
- •Unstable or serious illness (e.g. kidney, liver, biliary, GIT, heart conditions, diabetes, thyroid gland function, malignancy, lung conditions, chronic asthma, mood disorders or neurological disorders such as MS)*
- •Currently taking medications that may affect BDNF such as antidepressants or anxiety medications, or have taken within the previous 6 months
- •Prescribed/receiving anticoagulation therapy (e.g., coumadin, heparin)
- •Females who are either trying to conceive, pregnant or lactating
- •Any chronic menstrual disorders or menopausal changes
- •Alcohol consumption exceeding 21 drinks/week
- •Active smoker/e-cigarettes/nicotine use, use recreational drugs
- •Any chronic gastrointestinal problems
- •History of eating disorders
- •Serious mood disorder
- •Hypotensive (blood pressure less than 90mm/60mmHg) or hypertensive (blood pressure greater or equal to 140/90mmHg)
- •Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion
- •Participants who have participated in any other related clinical study during the past 1 month
- •*An unstable illness is any illness that is currently not being treated with a stable dose of medication or is fluctuating in severity. A serious illness is a condition that carries a risk of mortality, negatively impacts quality of life and daily function and/or is burdensome in symptoms and/or treatments.
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