Prediction of Intraoperative Adhesions Before CS

Not yet recruiting

• Conditions: Abdominal Adhesion

• Registration Number: NCT06164522
• Lead Sponsor: Assiut University

Brief Summary

To predict the presence of intra-abdominal adhesions among women undergoing repeated cesarean section using several parameters.

Detailed Description

One of the most frequently performed surgical procedures globally is cesarean delivery (CD). Cesarean delivery rate is increasing, which raises the prevalence of intra-abdominal adhesions . The rate of intra-abdominal adhesions is 24-83% . Adhesions cause various postoperative complications, including intestinal obstruction, pelvic pain, dyspareunia, infertility, visceral injury, delayed delivery of the newborn , prolong surgical duration, increase bleeding amount and the incidence of hysterectomy . For these reasons, obstetricians always want to identify the possible extent of adhesions before cesarean section. Although to date there was no reliable technique to predict adhesions in women undergoing repeat CD .

Methods used in the evaluation of adhesions include the previous cesarean scar features, pigmentation, width and length , ultrasound sliding sign has been used in predicting pelvic endometriosis ,Baron et al. ,used the sliding sign in predicting adhesions in women undergoing repeat CD, also Stretch marks are a type of skin alteration that occur during pregnancy.

To ensure better surgical outcomes and reduce morbidities, the accurate prediction of adhesion formations before cesarean section is important. This study aims to investigate the integration of multiple parameters, such as evaluating cesarean scars, ultrasound sliding sign, and striae gravidarum, to assess intra-abdominal adhesions. We hypothesize that employing a combination of these parameters will yield superior predictive capabilities compared to relying on a single parameter alone. By exploring a comprehensive approach to adhesion prediction, we endeavor to enhance the safety and efficacy of cesarean section procedures, ultimately improving maternal and fetal well-being.

Study Timeline

• Status Verified: 2023-12
• Study First Submitted: 2023-12-02
• Study First Submitted QC: 2023-12-02
• Study First Posted: 2023-12-11
• Last Update Submitted: 2023-12-14
• Last Update Posted: 2023-12-20
• Study Start: 2024-01-01
• Primary Completion: 2025-01
• Study Completion: 2025-02-28

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 146

Inclusion Criteria

1. Pregnant women aged from 18 to 35 years
2. Women with at least one previous C-section
3. Gestational age (≥36 weeks)
4. Planned elective cesarean section

Exclusion Criteria

1. primigravida
2. Gestational age (<36 weeks)
3. Pregnant woman who had developed wound site infections following prior cesarean section

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Predicting presence of intra-abdominal adhesions among women undergoing repeated cesarean section using several parameters.	From January 2024 to February 2025	Detection of intra-operative adhesions before repeated cesarean section by history, examination and ultrasound