What are the effects of training on thought processes and symptoms in persons with depression?

Not Applicable

• Conditions: Major depressive disorder, generalized anxiety disorder; Mental and Behavioural Disorders

• Registration Number: ISRCTN58765041
• Lead Sponsor: Instituto Superior da Maia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-24
• Last Update Posted: 9 January 2023
• Study Completion: 2023-12-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

1. Over 18 years old.
2. Be fluent in Portuguese.
3. Normal or corrected normal vision.
4. Meet the criteria for Major Depressive Disorder or Generalized Anxiety Disorder for inclusion in the clinical groups. In turn, for the inclusion in the Healthy Adults group participants must not have any psychological diagnose.

Exclusion Criteria

1. Meet the criteria for substance abuse, bipolar disorder, and any psychotic disorder or symptoms.
2. Active suicidal ideation or a previous suicide attempt.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Depression symptoms are measured with the Patient Health Questionnaire-9, in all groups and conditions, in the screening, baseline, intervention, and follow-up stages to assess the development of depressive symptoms.<br> 2. Anxiety symptoms is measured using the Generalize Anxiety Disorder-7 in all the sessions and in all groups and conditions.<br> 3. Attentional bias is measured using a Dot-Probe Task in the baseline, intervention, and follow-up stages.<br> 4. Interpretation bias is measured with the Scrambled Sentences Test at baseline, intervention, and follow-up stages.<br> 5. Working memory is measured with the N-back task at baseline, during intervention and follow-up stages.<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Emotion regulation strategies are measured with the Regulation Emotion System Survey at baseline, during intervention and follow-up stages.<br> 2. Memory bias is measured with the Self-Referent Encoding Task at baseline, during intervention and follow-up.<br>