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Evaluate Performance of Callisto Eye vs. Wavetec AnalyzOR

Completed
Conditions
Cataract
Interventions
Device: CALLISTO eye
Device: Wavetec AnalyzOR
Registration Number
NCT06216067
Lead Sponsor
Chesapeake Eyecare and Laser Center, LLC
Brief Summary

The goal of this clinical trial is to evaluate two separate operating room cataract measuring tools in predicting the residual astigmatism (prediction error) in patients with corneal astigmatism.

The main question it aims to answer is:

Show the refractive predictability comparing the use of Operating Room cataract toric lens placement tools against the standard manual technique.

Participants will be implanted with the TECNIS Toric II IOL Lens Model ZCU; the second eye, if applicable, is to be implanted within 45 days of the first-eye surgery.

Researchers will compare two Operating Room cataract lens placement tools: the Zeiss CALLISTO vs. the Wavetec AnalyzOR to determine refractive predictability.

Detailed Description

To evaluate two separate operating room cataract measuring tools in predicting the residual astigmatism (prediction error) in patients with corneal astigmatism (maximum allowable up to 3.0D) comparing the ZEISS CALLISTO eye and the Wavetec AnalyzOR at the one-month post-operative visit. Both surgery rooms will be using Veracity, IOL Master and Zeiss Opmi Lumera i Operating Room Microscopes. Operating Room #1 will be utilizing the ZEISS CALLISTO eye for axis alignment, along with Veracity and IOL Master for lens selection, and Operating Room #2 will be utilizing the Wavetec AnalyzOR for lens selection and axis alignment. Procedure times for the ZEISS CALLISTO eye and the Wavetec AnalyzOR will be obtained by using a start/stop watch, including phakic power calculation and toric positioning. In addition, the suction on (start of LenSx), treatment time of LenSx in seconds, suction off (end of LenSx), start time of primary incision, the beginning of Phaco, end of phaco, CDE (Combined Diffused Energy) total and the end time of procedure will all be documented. All times will be analyzed and compared between Operating Room #1 and Operating Room #2.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
36
Inclusion Criteria
  • Unilateral or bilateral cataract extraction with single piece hydrophobic acrylic posterior capsular intraocular lens correcting astigmatism.
  • Clear intraocular media other than cataract.
  • Willing and able to complete all required postoperative visits.
  • Able to comprehend and sign a statement of informed consent in English.
Exclusion Criteria
  • Ocular disease or pathology that, in the opinion of the Investigator, will affect the post-operative visual acuity and manifest refraction.
  • Prior intraocular or corneal refractive surgery, corneal transplant, or retinal detachment.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Group 1 (Operating Room #1) CALLISTO eyeCALLISTO eyeGroup 1 (Operating Room #1) will have preoperative measurements with the IOL Master 700 and lens selection will be based on Veracity. The subjects in group 1 will have LenSx surgery and placement of the lens will be based on the CALLISTO eye.
Group 2 (Operating Room #2) Wavetec AnalyzORWavetec AnalyzORGroup 2 (Operating Room #2) will also have preoperative measurements with the IOL Master700, but lens selection will be based on the Wavetec AnalyzOR. The subjects in group 2 will have LenSx surgery and placement of the lens will be based on the Wavetec AnalyzOR.
Primary Outcome Measures
NameTimeMethod
Diopters of Residual Cylinder1 Month postoperatively from implantation of intraocular lens

Diopters of Residual Cylinder at Month 1 with an upper boundary and lower boundary of +0.50 D and - 0.50 D

Secondary Outcome Measures
NameTimeMethod
Refractive predictability of the IOL (absolute difference between MRSE and target MRSE)Month 1

MRSE within 0.25, 0.50, 0.75, 1.00 of target

Uncorrected Distance Visual Acuities Achieved - SnellenMonth 1

Achievement of UCDVA of 20/20, 20/25, 20/30, 20/40 or better

Accuracy of Residual Astigmatism (Predictive Error)Month 1

Residual Astigmatism of +/- 0.25 D or less, +/- 0.75 D or less, +/- 1.00 or less

Procedure and Operating Room TimeProcedure time (up to 2 minutes)

Suction on (start of LenSx), treatment time of LenSx in seconds, Suction off (end of LenSx)

Operating Room TimeOperating Room Time (up to 30 minutes)

Start and end time of matching reference image to microscope image, start time-primary incision, beginning of Phaco, end of Phaco, CDE (Combined Diffused Energy) Total, Start and end time of phakic power calculation, start and end time of toric positioning, end time of procedure

Trial Locations

Locations (1)

Chesapeake Eye Care and Laser Center, LLC

🇺🇸

Annapolis, Maryland, United States

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