The feasibility study for adenocarcinoma screening by novel urinary biomarker using protein fragments: a cross-sectional study

Not Applicable

Recruiting

• Conditions: adenocarcinoma (gastric cancer, colorectal cancer, or bile duct cancer)

• Registration Number: JPRN-UMIN000038400
• Lead Sponsor: niversity of Miyazaki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-31
• Study Completion: 2023-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Adenocarcinoma group 1. Patients who do not have the schedule for surgical treatment, endoscopic submucosal dissection, or endoscopic mucosal resection. 2. Patients who received chemotherapy or endoscpic treatment. 3. Patients who have proteinuria, positive urine sugar or urine occult blood in urinalysis. 4. Patients who have renal dysfunction (Serum levels of creatinine > 2.0 mg/dl). 5. Patients who have alcohol or drug dependence or who are suspected to have alcohol or drug dependence. 6. Patients who is pregnant or who is suspected to be pregnant. 7. Patients who was enrolled another clinical trial and was prescribed a study drug within one month. 8. Patients whose attending physicians consider to be inappropriate for this study. Disease control group 1. Patients who were not clinicaly diagnosed gastrointestinal inflammation by gastoroscopy or colonoscopy within 3 months or who were not clinicaly diagnosed cholelithiasis or colonic diverticulitis by CT within 6 months. 2. Patients who have proteinuria, positive urine sugar or urine occult blood in urinalysis. 3. Patients who have renal dysfunction (Serum levels of creatinine > 2.0 mg/dl). 4. Patients who have alcohol or drug dependence or who are suspected to have alcohol or drug dependence. 5-7. Same criterias as Adenocarcinoma group (6-8). Healthy controls 1. Those who have not received a medical check within one year. 2. Those who have abnormal findings in chest X-ray, blood test or urine test within one year of obtaining informed consent. 3. Those who have current malignant neoplasm other than lung squamous cell carcinoma, or past history of malignant neoplasm within 5 years. 4. Those who have alcohol or drug dependence or who are suspected to have alcohol or drug dependence. 5-7. Same criterias as Adenocarcinoma group (6-8).

Study & Design

• Study Type: Observational
• Study Design: Not specified