ovel surgical treatment approaches based on ontogenetic anatomy for vaginal and cervical cancer: TMMR, KMMR, EMMR, LEER and tLNE
- Conditions
- C53C52Malignant neoplasm of cervix uteriMalignant neoplasm of vagina
- Registration Number
- DRKS00015171
- Lead Sponsor
- niversitätsklinikum Leipzig
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 600
Patients with histologically proven cervical carcinoma FIGO stages I B to II B or Müllerian vaginal carcinoma FIGO stage I or II without clinical evidence of involvement of the urethrovesical wall.
OR: Patients with histologically proven cervical carcinoma FIGO stages IIB / vaginal carcinoma FIGO stage II suspect for urethrovesical wall involvement or cervical carcinoma FIGO stages IIIA, B, IVA / Müllerian vaginal carcinoma FIGO stages III, IVA. In theses cases, the patients must insist on surgical treatment even after consultation with an radio-oncologist for information about the standard therapy.
Compromised general condition (Karnowsky index < 80%) or other comorbidity rendering the necessary surgery an inacceptable risk. Physical or psychological inability to cope with the expected sequelae of the operation. Previous pelvic radiation.
Previous major pelvic surgery (excluding simple hysterectomy). Advanced tumors infiltrating derivatives of external somatic coelom. Neuroendocrine tumors.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method