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Clinical Trials/NCT04437355
NCT04437355
Completed
Not Applicable

Clinical, Functional and Radiological Outcome After Osteosynthesis of Ankle Fractures Using a Specific Provocation Test- a Combined Retro- and Prospective Study

Spital Limmattal Schlieren1 site in 1 country90 target enrollmentJuly 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ankle Fracture, Trimalleolar
Sponsor
Spital Limmattal Schlieren
Enrollment
90
Locations
1
Primary Endpoint
Functional outcome
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Patients who underwent operative treatment of an ankle fracture with or without following removal of the osteosynthetic material are examined by a specific ankle provocation test, a questionnaire and X-Rays to evaluate the clinical, functional and radiological outcome compared to a healthy control group

Detailed Description

The study includes all patients operated from 09.12.2012 to 31.12.2020. Patients will undergo an X-Ray at least two years after primary surgery or at least one year after removal of the osteosynthetic material. The patients operated from 09.12.2012 to date are therefore a retrospective cohort, the patients from to date until 31.12.2020 a prospective cohort. This method is used to achieve the highest possible number of patients in a define period of time with no alteration of surgical technique. All patients in the retrospective cohort are contacted at least 2 years after surgery (or 1 year after removal) via phone call or letter, informed about the study and asked to participate. In case of informed consent, they are invited to the study site. They are asked to complete the questionnaires and they undergo X-Ray of the affected and the non-affected ankle. All patients in the prospective cohort are informed about the study and asked to participate in the outpatient clinic. In case of informed consent, they are invited to the study site at least 2 years after surgery. They are asked to complete the questionnaires and they undergo na X-Ray of the affected and non-affected ankle.

Registry
clinicaltrials.gov
Start Date
July 1, 2018
End Date
December 31, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Spital Limmattal Schlieren
Responsible Party
Principal Investigator
Principal Investigator

Prof Urs Zingg

Head of Department of surgery

Spital Limmattal Schlieren

Eligibility Criteria

Inclusion Criteria

  • Age older than 18 and younger than 51 years
  • Operative treatment of an ankle fracture
  • Time operation to follow up: at least 2 years
  • Time removal of osteosynthetic material to follow up: at least 1 year
  • Time operative treatment to removal of the osteosynthetic material: at least 9 months
  • Informed Consent as documented by signature (Appendix: Informed Consent Form)

Exclusion Criteria

  • Other pathologies of the lower limb of the affected and/or non-affected side (fractures, pre-existing arthrosis or operative treatment of the affected and/or non-affected limb)
  • Pre-existing vascular (peripheral arterial disease, diabetes) or neurological diseases of the lower extremities
  • Women who are pregnant
  • Prevalence of an infection of the implanted osteosynthetic material

Outcomes

Primary Outcomes

Functional outcome

Time Frame: 24 months after initial operation

This outcome will be compared with a group of adults matching in terms of gender and age. Measured by: - three questionnaires (quality of life, possible movement, restrictions in daily life etc.)

Secondary Outcomes

  • Clinical outcome 2(24 months after initial operation)
  • Clinical outcome 1(24 months after initial operation)
  • Clinical outcome 3(24 months after initial operation)

Study Sites (1)

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