Phase 1 study to examine the safety and dose-dependent effect of rapamycin topical medicine on perspiration in healthy volunteers
- Conditions
- hyperhidrosis
- Registration Number
- JPRN-UMIN000016525
- Lead Sponsor
- Department of Dermatology Graduate School of Medicine, Osaka University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 12
Not provided
1) A person who cannot carry out this treatment plan. 2) A person who have allergy to macrolide antibiotics. 3) A person who received oral administration of rapamycin or RAD001 within 12 months prior to the study entry. 4) A person who received topical administration of rapamycin or RAD001 within three days prior to the study entry. 5) A person who received topical treatment of aluminum chloride or iontophoresis within one months prior to the study entry. 6) A person who received local injection of Botox within three months prior to the study entry. 7) A person who received sympathectomy within 12 months prior to the study entry. 8) A person during pregnancy or lactation 9) A person who cannot undergo QSART and starch-iodine test 10) A person who were judged unsuitable for this study by the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method