Comparision of Anesthetic drug combinations Bupivacaine with clonidine and Levobupivacaine with clonidine used in nerve blocks for surgeries of upper limb
Phase 4
- Conditions
- ANAESTHESIA FOR UPPER LIMB SURGERIES
- Registration Number
- JPRN-UMIN000044438
- Lead Sponsor
- K.V.G. MEDICAL COLLEGE AND HOSPITAL DEPARTMENT OF ANAESTHESIOLOGY
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
1.Patient refusal for procedure 2.Any bleeding disorder or patient on anticoagulants 3.Neurological deficits involving brachial plexus 4.Patients with allergy to local anaesthetics 5.Local infection at the injection site 6.Patients on any adrenoreceptor agonist or antagonist therapy 7.Patients weighing less than 35kgs 8.Body mass index >35 9.Pregnant women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measure the Onset and duration of action between combination of 0.25% Bupivacaine with Clonidine and 0.25% Levobupivacaine with Clonidine in Supraclavicu;ar Brachial plexus block for upper limb surgeries. Onset was measured every minute after giving supraclavicular brachial plexus block Duration was measured until complete recovery from supraclavicular brachial plexus block using Bromage scale
- Secondary Outcome Measures
Name Time Method 1. Hemodynamic changes mainly systolic blood pressure, diastolic blood pressure, Mean arterial blood pressure and Peripheral oxygen saturation SpO2 are measured Intraoperatively every 5 minutes and Postoperatively every hourly upto 24 hours between the study groups 2.Postoperative Assessment of pain with the use of Visual analogue scale was measured every hourly upto 24 hours. 3. Occurance of any adverse events were notes